Bacopin Extract

Indications and Usage

 
The effect of Morinda officinalis How, a Chinese traditional medicinal plant, on the DRL **-s schedule in rats and the forced swimming test in mice.
Pharmacol Biochem Behav. ***2 May;*2(**2):****3.
The present study observed the antidepressant-like action of the medicinal plant Morinda officinalis. The plant extract (****0 mg/kg), similar to clinically effective antidepressant drug desipramine (***0 mg/kg), significantly reduced response rate and efficiency ratio while at the same time increasing reinforcement rate. In the forced swimming test in mice, the plant extract (*0 mg/kg), like the effect of desipramine (*0 mg/kg), also elicited a significant reduction in the duration of immobility. A tendency to this phenomenon could be seen at the dose of **0 mg/kg. Meanwhile, Morinda officinalis extract, in the effective doses for the forced swimming test, had no effects on spontaneous motor activity in mice. These findings provide further support for the conclusion that Morinda officinalis extract possesses the antidepressant effect.

Evaluation of the hypoglycemic and anti-oxidant activities of Morinda officinalis in streptozotocin-induced diabetic rats.
Singapore Med J. ***2 Feb;*3(2):*****5.
The aim was to investigate the hypoglycemic and anti-oxidant activities of the dried roots of Morinda officinalis in streptozotocin-induced diabetic rats. An ethanolic extract of the dried roots of Morinda officinalis and its three fractions (ethyl acetate, n-butanol and water) were obtained. We evaluated the hypoglycemic effects of three different single doses of the crude extract and its fractions in normal and diabetic rats for three hours after administration. Administration of the extract at **0 mg/kg twice daily for *0 days to the diabetic rats was also carried out.The effects of the **-day treatment on the fasting serum glucose, insulin, total cholesterol, triglycerides, body weight, food intake, fluid intake, hepatic superoxide dismutase (SOD), catalase (CAT) activities, reduced glutathione (GSH), thiobarbituric acid reactive substances (TBARS) and renal TBARS levels were monitored. In the three-hour dose response study, the crude ethanolic extract reduced the fasting serum glucose levels of the diabetic rats significantly at **0 mg/kg but increased those of the normal rats significantly at **0 mg/kg only. The water fraction demonstrated a dose dependent hypoglycemic effect in the diabetic rats whereas the n-butanol fraction increased the fasting serum glucose levels of the diabetic rats significantly at *0 mg/kg only within three hours after administration.The **-day oral administration of the extract reduced the fasting serum glucose, hepatic and renal TBARS level and significantly increased the hepatic SOD and CAT activities as well as GSH levels. The results indicate that the dried roots of Morinda officinalis possess hypoglycemic, hyperglycemic and anti-oxidant properties.
Package:
1kg/bag, 5kg/bag, *5kg/drum, double layers plastic bags inside.
 

Storage Situation:
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.