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GDC-0810(ARN-810) cas no 1365888-06-7

China

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タイトルまたは説明

Chemical Information

Product Name GDC-0810(Brilanestrant,ARN-810)
Iupac Chemical Name (E)-3-(4-((E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid 
Synonyms Brilanestrant;GDC-0810;GDC 0810;GDC0810;ARN-810;ARN 810;ARN810 
Molecular Formula C26H20ClFN2O2 
Molecular Weight 446.90 
Smile O=C(O)/C=C/C1=CC=C(/C(C2=CC3=C(NN=C3)C=C2)=C(C4=CC=C(F)C=C4Cl)/CC)C=C1
InChiKey BURHGPHDEVGCEZ-KJGLQBJMSA-N
InChi InChI=1S/C26H20ClFN2O2/c1-2-21(22-10-9-20(28)14-23(22)27)26(18-8-11-24-19(13-18)15-29-30-24)17-6-3-16(4-7-17)5-12-25(31)32/h3-15H,2H2,1H3,(H,29,30)(H,31,32)/b12-5+,26-21+
Cas 1365888-06-7

Technical Data

Appearance crystalline solid 
Purity 98% by HPLC 
Solubility Soluble in DMSO 
Storage 3 years -20ºCpowder 6 months-80ºCin solvent 
Shipping Condition Shipped under ambient temperature 
Quality control  

Description

GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (SERD) that is designed to bind to the estrogen receptor to limit its function. In addition, when SERDs bind to the estrogen receptor, they may be able to change the shape of the receptor in such a way that the cell eliminates it by degradation.

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Wuhan Sun-shine Bio-technology Corporation Limited

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Wuhan Sun-shine Bio-technology Corporation Limited

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Wuhan, Other, China,

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