Ibuprofen

タイトルまたは説明

Ibuprofen is from iso-butyl-propanoic-phenolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for relieving pain, alleviating fever,[1] and reducing inflammation.

Ibuprofen has an antiplatelet effect, though it is relatively mild and somewhat short-lived compared with aspirin or prescription antiplatelet drugs. In general, ibuprofen also has a vasodilation effect. Ibuprofen is a 'core' medicine in the World Health Organization's Model List of Essential Medicines necessary to meet the minimum medical needs of a basic healthcare system.

Ibuprofen was derived from propanoic acid by the research arm of Boots Company during the ***0s and patented in ***1. Originally marketed as Brufen, ibuprofen is available under a variety of popular trademarks, including Motrin, Nurofen, Advil, Nuprin and many others. Generic formulations are available as well.
 

Ibuprofen has a dose-dependent duration of action of around four to eight hours, which is longer than suggested by its short half-life. Onset of analgesia (time to effect) is *4.5 minutes using liquigel format orally. The recommended dose varies with body mass and indication. A dose of **0 mg per dose and ***0 mg per day is considered the maximum amount for over-the-counter use in the United States.

Unlike aspirin, which breaks down in solution, ibuprofen is stable, thus it can be available in topical gel form, which is absorbed through the skin, and can be used for sports injuries, with less risk of digestive problems.