Lentinan for Injection

タイトルまたは説明

LENTINAN FOR INJECTION 

A non-toxic anti-tumor polysaccharide from the shitake mushroom. In Japan, Lentinan, an extract from the mushroom has been used against colorectal and stomach cancer, often in conjunction with other treatment such as chemotherapy, and Japanese researches have presented data supporting this use. Like most of the other polysaccharide drugs, Lentinan appears to be an immunostimulant. Almost all of the Japanese studies have used injected lentinan, so it is very unclear whether eating shitake mushrooms could have a beneficial effect aside from the considerable culinary virtues.

Pharmacokinetics: 

After injection, Lentinan is rapidly and completely absorbed. Peak plasma concentrations are reached within one hour and elimination takes place with a half-life of 1.9 hours. It is distributed in the liver, the spleen, the lungs, the kidneys and so on and it is eliminated almost via urine.

Indications: 

Lentinan is indicated for many malignancies, especially for digestive and 

respiratory tract cancers. It can coordinate the action of chemotherapy, 

improve life quality and prolong survival time.

Dosage and administration: 

1. Lentinan 1 mg (1 vial) dissolved in 2mls injection water, then put into 

**0ml saline or 5% Glucose for intravenous drip. 

2. Lentinan 1 mg dissolved in ****0ml saline 5% Glucose saline for 

intravenous injection. 

3. Lentinan **4 mg dissolved in ****0 ml saline for direct injection in 

pleurae or peritoneum.