タイトルまたは説明

Povidone C*5, C*0, K**5, K*9/*2, K*0, K*0D (injections, binder, solubilizer)

Wet granulation binder

Prescription to a wet granulation binder, "bonding", and thus improve its compressibility and fluidity. This is not only the physical properties of the tablet plays an important role, but also for tablet bioavailability and efficacy also has a decisive influence. Plasdone ® Povidone-series is the preferred efficient wet granulation binder ISP companies provide Plasdone ® povidone products are for each specifically tailored to meet the different needs. Wet granulation binder Plasdone ® Series

Typical tradename Pharmacopeia (Mw) of Typical Viscosity (mPa.s)
Placdone ® K**9/*2

Povidone

"The United States Pharmacopoeia"

"European Pharmacopoeia"

"Japanese Pharmacopoeia"
*8 **0 2.5
Placdone ® K*5 ****0 2.0
Placdone ® K*0 ******0 *5.0
Placdone ® K**0D ******0 *5.0
Placdone ® S***0

Copovidone,

"European Pharmacopoeia"


****0
2.5

1 average molecular weight measured by a light scattering
(2) in deionized water was treated with 5% BrookfieldLVT viscometer (measured in *0r/min *5).

Plasdone ® K**9/*2 (povidone povidone USP, European Pharmacopoeia, Japanese Pharmacopoeia)

Plasdone ® K**9/*2 wet granulation is generally considered universal binders, because the viscosity is low, so easy to use, in the water and all approved pharmaceutically acceptable solvents are easily dissolved.
Table 2 Formulation blanks lactose, lactose blank as described in Figure 2 Plasdone ® K**9/*2 has high adhesion.