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SNS-032

China

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Bioactive small molecules

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製品仕様

CAS No. : - Other Names : - MF : - EINECS No. : - Type : - Grade Standard : - Usage : - Brand Name : - Purity (%) : -

タイトルまたは説明

Chemical Information

Product Name SNS-032(BMS-387032)
Iupac Chemical Name N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide 
Synonyms SNS-032,BMS-387032 
Molecular Formula C17H24N4O2S2 
Molecular Weight 380.53 
Smile C(C)(C)(C)C1=CN=C(O1)CSC1=CN=C(S1)NC(=O)C1CCNCC1
InChiKey OUSFTKFNBAZUKL-UHFFFAOYSA-N
InChi InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)
Cas 345627-80-7

Technical Data

Appearance off-white solid 
Purity 98% 
Solubility 5mg/ml in DMSO 
Storage 3 years -20ºCpowder 
Shipping Condition Shipped under ambient temperature 
Quality control  

Description

SNS-032 has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. Phase 1.

お問い合わせ

連絡先担当者: Winne

会社:Wuhan Sun-shine Bio-technology Corporation Limited

住所:Wuhan, Other, China,

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Winne < Wuhan Sun-shine Bio-technology Corporation Limited >
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