タイトルまたは説明
Sodium chloride is an electrolysis supplement agent; sodium and
chloride are important electrolysis for the human body and mainly
exist in extracellular fluid, which play an important role in
maintaining normal volume of blood and extracellular fluid and
osmosis pressure. Normal serum sodium concentration is about
**5~**5mmol/L, with a *2 percent of the plasma cation and a *0
percent of total osmosis pressure, so the quantity of plasma sodium
play a decisive role for the osmosis pressure; normal serum
chloride concentration is about *8~**6mmol/L; sodium and chloride
in human body are mainly adjusted by hypothalamus, lobus posterior
hypophyseos and kindney so as to maintain the stability of body
fluid volume and osmosis pressure. [Pharmacokinetics] Sodium
chloride enter the blood circulation directly after injected by
intravenous, and distribute widely in the human body, and mainly
exist in extracellular fluid. Both sodium and chloride can be
filtrated by glomerule, and partially be absorbed by renal tubules.
Sodium chloride is mainly excreted through urine by kindney, some
is excreted through sweat. [Indications] It is indicated for
dehydration caused by all kinds of cases, including hypoosmolality,
isotonia and hypertonicity; also for the coma caused by
hypertonicity non-ketosis diabetes as the administration of
isotonia and hypoosmolality sodium chloride can correct the
dehydration and hyperosmotic state;it is also indicated for
low-chloride metabolic alkali poisoning; and external use sodium
chloride can be used to wash the eyes and wounds; it also can be
used for the induction of labor with water bag. [Dosage and
administration] [Side-effect] (1)Overdose and over-rapidness of
infusion may lead to retention of water and sodium, cause hydrops,
increased blood pressure, increased heart rate, oppressed feeling
in chest, breath hard, even left ventricular failure. (2)Overdose
and over-rapidness of injection low-concentration sodium chloride
may lead to haemolysis, cerebral edema and so on.
[Contraindication] (1)diabetes ketosis acidose; (2)hyperglycemia
non-ketosis hyperosmotic state; [Attention] (1)Avoid using the
medicine for the following cases 1.hydropsy, such as the kidney
syndrome, liver cirrhosis, hydroperitoneum, congestive
heart-failure, acute left ventricular failure, hydrocephalus,
idiopathic edema and etc.;2. acute kidney failure oliguria stage,
chronic kidney failure decreased urine and bad reaction for
diuretic;3. hepertension;4. hepo-potassium. (2)According to the
clinical requirements, examine the concentration of sodium,
potassium, chloride in the serum; examine acid and alkali
concentration equality index ; examine the renal function, blood
pressure and cardio-pulmonary function. [Pregnancy and Lactation]
Forbid to use the sodium chloride injection for the patients with
hypertension of pregnancy syndrome. [Pediatric Use] The dosage and
the speed should be controlled strictly. [Geratology]The dosage and
the speed by drip should be controlled strictly. [Interaction]Pay
attention to the incompatibility of drugs when Sodium Chloride
Injection used as solvent or dilution. [Overdose]Overdose may lead
to hypernatremia and hypo potassium, also may lead to the missing
of bicarbonate. [Specification] **0ml:4.5g [Storage]Store in the
closed container. [Package]glass injection bottle or plastic bottle
[Expiry date]two years
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