Spirodiclofen TC

タイトルまたは説明

spirodiclofen (**8)
Acaricide
 
 
 
 
 
 
NOMENCLATURE
Common name spirodiclofen (BSI, pa ISO)
IUPAC name *-(2,*-dichlorophenyl)**-oxo**-oxaspiro[4.5]dec**-en**-yl 2,*-dimethylbutyrate 
Chemical Abstracts name *-(2,*-dichlorophenyl)**-oxo**-oxaspiro[4.5]dec**-en**-yl 2,*-dimethylbutanoate 
CAS RN [**********8]  Development codes BAJ***0 
 
PHYSICAL CHEMISTRY
Mol. wt. **1.3 M.f. C*1H*4Cl2O4  Form White powder. V.p. 3´*0*4 mPa (*0 °C) KOW logP = 5.8 (pH 4, *0 °C) Henry 2.5´*0*3 Pa m3 mol*1 (calc.) Solubility In water *0mg/l (pH 4, *0 °C). 
 
 
APPLICATIONS
Mode of action Interferes with mite development. Uses Under development for control of mite pests such asPanonychusspp.,Phyllocoptrutaspp.,Brevipalpusspp., andAculusandTetranychusspecies, at *****0 g/***0 l. For use in citrus, pome fruit, stone fruit, grapes and nuts.Formulation types SC; WG. Selected products: 'Envidor' (Bayer CropScience)
 
MAMMALIAN TOXICOLOGY
Oral Acute oral LD*0 for male and female rats >***0 mg/kg. Skin and eye Acute percutaneous LD*0 for male and female rats >***0 mg/kg. Non-irritating to skin and eyes (rabbits). Not a skin sensitiser (SC formulation, guinea pigs). Inhalation (4 h) for rats >***0 mg/m3. NOEL NOAEL (*2 mo) for dogs *0 ppm. Other No teratogenic potential (rats and rabbits); *-generation rat study revealed no evidence of a primary reprotoxic potential; no evidence of genotoxic or mutagenic potential. 
 
ECOTOXICOLOGY
Birds Acute oral LD*0 >***0 mg/kg. Fish LC*0 (*6 h) >*8 mg a.i. (as **0SC)/l Daphnia EC*0 (*8 h) >**0 mg a.i. (as **0SC)/l Bees LD*0 (oral and contact) >**0mg/bee. Worms LC*0 for Eisenia foetida >***0 mg/kg dry soil. Other beneficial spp. Non-toxic to ladybirds (Coccinella septempunctata) at **0 g/ha. Slightly harmful to predatory mites under field conditions (**0SC; IOBC scale). No negative effect on microbial mineralisation. 
 
ENVIRONMENTAL FATE
Soil/Environment DT*0 in soil 0.**5.5 d. No leaching problem (lysimeter study).