タイトルまたは説明

Zinc Pyrithione was first reported in the ***0s. It has two pyridine-derived chelating ligands bound to zinc via oxygen and sulfur atoms. In cosmetics and personal care products, Zinc Pyrithione functions as an antidandruff agent, antimicrobial agent, hair conditioning agent, and preservative.

Zinc pyrithione has been used, as an anti-dandruff agent, for more than *0 years, in concentrations up to **2%. It is effective against a wide variety of pathogenic bacteria. Its other applications include treatments of psoriasis, eczema, ringworm, fungus, athletes’ foot, dry skin, and atypical dermatitis Due to its low solubility in water, zinc pyrithione is suitable for use in outdoor paints and other products that provide protection against mildew and algae. Its decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight.Antifungal effect of Zinc prithione is most likely lies in the ability of an un-ionized pyrithione molecule to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.