Description
Ferulic acid
Item: NL***2
Grade: *0%, *5%
CAS NO.: *******4
Molecular formula: C*0H*0O4
Melting point: ******2 °C
Botanical origin: Oryza sativa L.
Appearance: Fine white powder
Ferulic acid is a hydroxycinnamic acid, a type of organic compound.
It is an abundant phenolic phytochemical found in plant cell wall
components such as arabinoxylans as covalent side chains. It is
related to trans-cinnamic acid. As a component of lignin, ferulic
acid is a precursor in the manufacture of other aromatic
compounds.
Ferulic acid, like many natural phenols, is an antioxidant in vitro
in the sense that it is reactive toward free radicals such as
reactive oxygen species (ROS). ROS and free radicals are implicated
in DNA damage, cancer, accelerated cell aging. Animal studies and
in vitro studies suggest that ferulic acid may have direct
antitumor activity against breast cancer and liver cancer. Ferulic
acid may have pro-apoptotic effects in cancer cells, thereby
leading to their destruction. Ferulic acid may be effective at
preventing cancer induced by exposure to the carcinogenic compounds
benzopyrene and *-nitroquinoline *-oxide. Note that these are not
randomized controlled trials done with human participants, and
therefore, the results of these studies may not be directly
applicable to human use.
If added to a topical preparation of ascorbic acid and vitamin E,
ferulic acid may reduce oxidative stress and formation of thymine
dimers in skin. There is also a small amount of research showing
oral supplements of ferulic acid can inhibit melanin production in
the process of skin whitening.