Description

Povidone Iodine Solution 5% , 7.5%, *0% Povidone Iodine raw material BP USP Red brown liqiud Use: Povidone-iodine (PI, Betadine) is routinely used as a preoperative topical antiseptic in cataract surgery as it has been shown to reduce the incidence of postoperative endophthalmitis. However, the concentration used clinically is variable. In vitro studies have shown that PI is paradoxically more effective at lower concentration. This study was undertaken to determine if this effect was reproducible in vivo. Methods: Aprospective randomised double blind study was carried out in the ophthalmic theatre in a district general hospital. **5 patients attending for routine cataract surgery were randomly allocated to have their conjunctival fornices irrigated preoperatively with either PI 1% (group A) or PI 5% (group B). Conjunctival swabs were taken, in identical fashion, both before and 1 minute after irrigation. The number and species of bacterial colonies cultured from each swab was counted. The difference in the median number of bacterial colonies from pre-irrigation to post-irrigation cultures was then compared between the groups. Packing in *5kg coloured drum, or ***0ml bottle and in cartons. Packaging and storage: Preserve in tight, light-resistant containers.