Description
Eucommia Leaf Extract*- chlorogenic acid ****9% (HPLC)
Product Name : Eucommia Leaf Extract
Specification: chlorogenic acid *5%,*0%,*8%,*9% (HPLC)
Molecular formula: C*6H*8O9
CAS No: *******9
Einecs No:********6
Molecular weight: **4.*1
Solubility: Good solubility in water
Melting point:******9
Appearance: Fine crystal powder
Color: White
Specific Rotation [α]: **6(c=1, H2O)
Chlorogenic acid, an ester of caffeic acid and quinic acid, is a
major phenolic compound in coffee, but is also found widespread in
plants and can be isolated from the leaves and fruit . This
compound, long known as an antioxidant, also slows the release of
glucose into the bloodstream after a meal.
Biological importance
This acid is an important factor in plant metabolism. It is also an
antioxidant and an inhibitor of the tumor promoting activity of
phorbol esters; at concentrations as high as **0ug/L, does not
inhibit the *-lipoxygenase activity of ionophore-stimulated human
polymorphonuclear leukocytes.
Chlorogenic acid and caffeic acid are antioxidants in vitro and
might therefore contribute to the prevention of Type 2 Diabetes
Mellitus and cardiovascular disease .
Chlorogenic acid is an important factor in plant metabolism. It is
also an antioxidant and an inhibitor of the tumor promoting
activity of phorbol esters.Chlorogenic acid, at concentrations as
high as **0 um, does not inhibit the *-lipoxygenase activity of
ionophore-stimulated human polymorphonuclear leukocytes.
Chlorogenic acid, an ester of caffeic acid and quinic acid, is a
major phenolic compound in coffee; daily intake in coffee drinkers
is 0.**1 g. Chlorogenic acid and caffeic acid are antioxidants in
vitro and might therefore contribute to the prevention of
cardiovascular disease.
Chlorogenic acid has been proven in animal studies in vitro to
inhibit the hydrolysis of the glucose**-phosphate enzyme in an
irreversible fashion. This mechanism allows chlorogenic acid to
reduce hepatic glycogenolysis (transformation of glycogen into
glucose) and to reduce the absorption of new glucose. In addition,
in vivo studies on animal subjects have demonstrated that the
administration of chlorogenic acid lessens the hyperglycemic peak
resulting from the glycogenolysis brought about by the
administering of glucagen, a hyperglycemiant hormone. The studies
also confirmed a reduction in blood glucose levels and an increase
in the intrahepatic concentrations of glucose**-phosphate and of
glycogen.
Chlorogenic acid can be used as anti-infectious active ingredient,
it has wide anti-virus, anti-bacteria effects, and has relatively
lower toxicity and side-effects. It has obvious anti-infectious
effects, and does not like to lead Anti-microbial Resistance.
Due to its obvious anti-infectious effects, it not only can be used
in pharmaceutical field but can be used widely in many other fields
like food, feed additives, cosmetics also.
