With the name: Mi mida zolam injection English: Mida zolam
Injection Hanyu Pinyin name: Mida zolun Zhusheye the main component
of this product: microphone mida zolam hydrochl oride (hydrogen
maleate) Chemical Name: 8 - chloro - 6 - (2 - fluoro
-phenyl)
*1 - methyl*4H-imidazo [1,*-a] [1,4] formula: the
hydrochloride C*8H*3ClFN3 · HCl Molecular Weight: **2.2 Molecular
Formula: maleate C*8H*3ClFN3 · C4H4O4molecular
weight: **1.8 Properties】 colorless to pale yellow clear
liquid.Pharmacology
and toxicology animal test results show that this product has a
significant sedative, muscle relaxant, anticonvulsant, anxiolytic
pharmacological effects.The
results of acute toxicity in mice, intravenous LD*0 of the male
*1.*2mg/kg, the female *3.*6mg/kg; intraperitoneal LD*0 of, male
**0.*5mg/kg, female **2.*2mg/kg.Pharmacokinetics]
According to the literature, the product absorption of
intramuscular administration of quickly and completely,
bioavailability more than *0%.This
product is completely in the body is metabolized, the main
metabolite is hydroxy mida zolam, and then quickly glucuronide was
inactive metabolites.*0% to *0% of the dose
excreted by the kidneys.The
steady-state volume of distribution of the intravenous
administration of up to *0 to *0 liters, about *5% of the plasma
protein binding rate, blood clearance rate of **0 to **0ml /
half-life of 1.5 to 2.5 hours.
