Description
Function
 1, Anti-oxidation; Myricetin is an
inhibitor of cyclooxygenase 1 (COX*1), cyclooxygenase 2 (COX*2) and
*-lipoxygenase (*-LOX);
2,
Antagonic action on platelet activating factor (PAF), demonstrating
pharmacological actions such as anti-thrombus, anti-myocardia
ischemia, improving the microcirculation and prophylaxis of artery
cirrhosis;
3,
Adjusting cholesterol level; In vitro research suggests that
myricetin in high concentration is capable of modifying LDL
cholesterol in a manner that enhances its uptake by white blood
cells.
4,
Decreasing blood sugar; It can be used as food additive for
diabetics;
5,
Protecting liver;
6,
Anti-inflammation and anti-infection;
7.
Acting as inhibitor of matrix metalloproteinase; It can be used for
prevention and treatment of cardiovascular disease and
tumor;
8. A
good dyeing agent.
Distribution
Myricetin is found in several foods such as
walnuts, onions, berries, herbs and red grapes.
Properties
Myricetin exerts a wide variety of biological
effects, including antioxidant and free radical-scavenging
activities. Reports indicate that myricetin has anti-cancer and
anti-inflammatory properties and may improve
bone-health.
Anticancer
Myricetin has strong anticancer and
antimutagernic properties, but it has been shown to promote
mutagenesis with the use of the Ames Test. Although the anticancer
property of myricetin has been attributed mainly to its antioxidant
action, it has additional protective mechanisms.
Anti-inflammatory
Myricetin has been shown to inhibit the
expression of tumor necrosis factor-alpha, a cytokine that promotes
the inflammatory response and is involved in inflammatory diseases.
Myricetin glucuronide is an inhibitor of lipoxygenase *-LOX and
cyclooxygenases COX*1 and Cox*2.
Heart
health
Myricetin and other flavonoids may improve heart
health by prevening LDL oxidation and reducing the uptake of
oxidized LDL by macrophages.
Diabetes
Studies showed that myricetin inhibits the uptake
of methylglucose by adipocytes, reduces oxidative injury in
diabetes related bone diseases and reduces glucose plasma level in
diabetic rats.
Brain
health
Myricetin may offer benefits to
person with brain diseases such as Parkinson and Alzheimers.
Myricetin inhibits ROS production caused by glutamate and reduces
glutamate-induced activation of caspase*3. Myricetin restored
dopamine level in laboratory animals with induced Parkinsonism.
Myricetin may also inhibit beta-amyloid fibril formation in
Alzheimer patients.
