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連絡先担当者 Frank
Suit B209, Bai Jiazhuang Commercial Center, No. 3, Bai Jiazhuang Rd., Beijing, Beijing
Zearalenone is rapidly absorbed following ingestion and is metabolized by the liver, intestinal mucosa, and gut microflora of pigs into the toxic metabolites α and β-zearalenol and the glucuronide conjugates of both compounds. α-zearalenol has about three-fold more estrogenic potency than zearalenone.
Zearalenone and its metabolites have been found in the plasma of a pig less than *0 minutes after consumption. The gastrointestinal uptake in swine after a single oral dose of *0 mg/kg body weight has been estimated to be *0 to *5%. Zearalenone and its metabolites are excreted in the feces, most within *2 hours of ingestion. Extensive cycling of zearalenone and its metabolites via enterohepatic circulation increases its biological half life significantly extending toxic exposure.
Calibrin-Z quickly adsorbs mycotoxins and significantly reduces gastrointestinal uptake. Sequestering the toxins in the intestinal lumen so they are not absorbed reduces the animal's exposure by a factor of *5.
