Description
Botanical source: Magnolia officinalis Rehd.et Wils. Biogenic
origin: Wild in central and southern China A compound found in
magnolia species holds exciting promise in the management of
anxiety, cancer, and other challenging conditions. Honokiol is a
bi-phenolic compound with the formula C*8H*8O2 and a relatively
small molecular weight of **6 grams/mole. This molecule is found in
several species of the genus magnolia including M. officinalis,
obovata, and grandifolia. It is an isomer of another compound also
found in magnolia materials called magnolol, which has ***0 times
the antioxidant potential of vitamin E. The dried bark of M.
officinalis usually has about **5% hanokiol and ***0% magnolol.
Magnolia Species and Traditional Use While magnolia species have
been incorporated in traditional healing systems throughout the
world, the barks of Chinese M. officinalis and Japanese M. obuvata
have become quite popular due to their verified levels of
phytochemicals like honokiol. The bark of M. officinale (houpa) is
often sought for incorporation in traditional Chinese formulas
addressing “chi stagnation”, asthma, anxiety, cancer, and digestive
disorders. China produces well over **0 tons of magnolia bark a
year. With its popularity comes the concern of over-harvesting
since the tree is killed during bark procurement. A positive side
to this is that the honokiol molecule is not very complex and is
easily synthesized through organic chemistry methods.
Pharmokinetics Honokiol appears to be non toxic, easily absorbed,
and systematically available. This is important since many
promising materials like Epigallocatechin Gallate (EGCG) are not
absorbed well in the digestive tract. Honokiol also avoids
immediate clearing by the liver (first pass effect) and crosses
blood barriers that often exclude other compounds.Honokiol has a
significant, long-lasting central muscle relaxation, inhibition of
the central nervous system, anti-inflammatory, antibacterial,
disease of the original microbial, anti-ulcer, anti-oxidation,
anti-tumor, morphine withdrawal response, inhibit platelet
aggregation and other pharmacological effects for the treatment of
acute enteritis. bacterial or amoebic dysentery. chronic gastritis.
Among them, the antibacterial effect of magnolol on the
Gram-positive bacteria, acid-resistant bacteria, filamentous fungi
have significant antimicrobial activity, a more significant
antibacterial effect on Streptococcus mutans, the strongest
inhibitory effect on Staphylococcus aureus. Clinically for the
elimination of the chest and abdomen full of nausea, sedation
central nervous system, athletes, muscle relaxants, anti-fungal,
anti-ulcer drugs Eucommia Ulmoides Extract Chlorogenic Acid ***8%
Banaba Leaf Extract Crosolic Acid ***8% Privet Leaf Extract Ursolic
Acid ****8%,*5% Honeysuckle FlowersExtract Chlorogenic Acid ***9%
Bitter Apricot Seed Extract Amygdalin ****8% Flax Seed Extract
secoisolariciresinol Diglucoside *0%，*0% Grape Skin Extract
Resveratrol *0%**8% Rhubarb Extract Emodin *0%,*8% Ampelopsis
Gressedentata Extract Dihydromyricetin *5%,*8% China Bayberry Bark
Extract Myricetin *5%**8% Grape Seed Extract OPC 5%**8% Eurycoma
Longifolia Extract 4:1,*0:1, **0:1 Shorthorned Epimedium Extract
Icariin ****8% Fructus Lycit Extract Lycium Barbarum
Polysaccharides *0%**0% Chinese Blueberry Extract OPC(Oligomeric
Proantho Cyanidins)*0%,*5%,*0% Magnolia Bark Extract Magnolol
*0%,*5%,*8% Honokiol *0%,*5%,*8% Honokiol +Magnolol *0,*8% Lotus
Leaf Extract Nuciferine 2% Ginseng Extract Total Ginsenoside
Ginseng Root *0%**0% Mulberry Leaf Extract *-
Deoxynojirimycin(*-DNJ) 1%**0%,*8% Tomato Extract Lycopene 5%**0%
Artemisia Annua Extract Artemisinin *8% Feverfew Extract
Parthenolide *5%**8% Polygonum Cuspidatum Extract Resveratro
*5%**8% Ligustrum lucidum Ait Extract Oleanic acid *8% Scutellaria
Root Extract Baicalin *0%**5% Swertia chirata extract Swertiamarin
****8% Olive leaf extract Hydroxytyrosol ***5% Olive leaf extract
Olives bitter glycosides ****0% gotu kola extract Asiaticoside
****0% gotu kola extract Madecassoside ****0% Macleaya cordata
Extract sanguinarine ****0% Macleaya cordata Extract cordata
Extract ****0% Green tea extract EGCG ****8% Tomato extract
Lycopene ***0% Rosehip extract Polypheo l0%,*0% Rosemary extract
Rosmarinic acid 2.***8% Peony Extract paeoniflori 5:1,*0:1,*0:1
****5%
