Description
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Hyaluronan is a medication prescribed for the treatment of
osteoarthritis. This treatment, sometimes called
viscosupplementation, is used for affected knee joints. It works
like the natural synovial fluid in the joint to cushion it and
provide lubrication to reduce pain and improve mobility. Patients
will typically try other treatment methods first before using this
drug.
Hyaluronic acid (also called Hyaluronan) is a component of
connective tissue whose function is to cushion and lubricate.
Hyaluronan occurs throughout the body in abundant amounts in many
of the places people with hereditary connective tissue disorders
have problems such as joints, heart valves and eyes. Hyaluronic
acid abnormalities are a common thread in connective tissue
disorders. Interestingly, they are also common biochemical
anomalies in most of the individual features of connective tissue
disorders such as mitral valve prolapse, TMJ, osteoarthritis, and
keratoconus.
Hyaluronic acid has been nicknamed by the press as the "key to the
fountain of youth" because it has been noted that at least some
people who ingest a lot of it in their diets tend to live to ripe
old ages. ABC News had a show on a village in Japan and hyaluronic
acid entitled, "The Village of Long Life: Could Hyaluronic Acid Be
an Anti-Aging Remedy?". (It should be noted that the people in the
ABC news show were thought to get high amounts of HA from starchy
root vegetables their natural diets. They were not taking
supplements.)
While a number of studies have linked abnormal levels of HA to
either connective tissue disorders (CTDs) or conditions common in
CTDs, such as premature aging, there are also a number of studies
on Pubmed noting associations of high levels of HA to some forms of
cancer. With HA as with other substances in the human body, such as
estrogen and cholesterol, there are most likely optimal levels, and
disease often occurs when these levels become out of range in
either direction. Low estrogen levels have been linked to bone
loss, while high estrogen levels have been associated with breast
cancer. High cholesterol levels have been linked to heart attacks
and stroke, while low levels have been linked to bleeding problems
and depression. HA has been studied less than either cholesterol or
estrogen, but the prudent path would be to assume that the body has
optimal levels of HA, as it does for cholesterol, estrogen and many
other substances.
As such, it is always prudent to consult your doctor before you
decide to take HA or any other type of supplement to make sure it
is an appropriate treatment for your particular health
condition.
