Sell Triclabendazole Bolus 900mg

Pharmacological action:
Triclabendazole binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.
Triclabendazole is specifically active against Fasciola, hepatica and F.gigantica.
The unique efficacy of Triclabendazole against the early immature and immature Fasciola stages makes this product particularly useful for the treatment of outbreaks of acute and subacute fasciolosis and for the strategic control of Fasciola infections. In addition, the efficacy against the 3 stages accelerates clinical recovery.
After oral administration, ****5% of the dose of triclabendazole is absorbed from the gastrointestinal tract. It is then rapidly metabolized to its sulphoxide and sulphone metabolites. The sulphoxide is thought to be the active moiety. In
cattle the sulphoxide and sulphone metabolites reached a Cmax of approx.*3 μg/ml and *6 μg/ml at *8 and *8 hours respectively. The vast majority of oral dose triclabendazole is eliminated in faces after 7 days.
Urinary excretion is minimal. Less than 1% is excreted in milk.

Dosage & Administration:
Like other anthelmintics a bolus can be administered per OS by hand balling gun or crushed mixed with water and drenched. The recommended dosage is *2 mg triclabendazole per kg body weight. Dosing guide is as follows:
Calves *0 to *5kg b.w 1 bolus
*5 to **0kgb.w 2 boli
**0kg to **5kg b.w 3 boli
Adult cattle Up to **0kg1 bolus1 bolus 4 boli
Dosage is increased over **0kg by one bolus for every additional *5kg body weight. Cattle grazing in fields contaminated with fluke eggs should be regularly treated every ***0 weeks, soon following diagnosis of sub-acute or acutrinfestation. Dosing of the entire herd is recommended.
Side-effects:Triclabendazole is very safe anthelmintic, which can be administered to stressed, sick or debilitated cattle of all ages. It can be used to treat pregnant cows. No contraindications are reported.
Precautions:Wash hands after use. Avoid contamination of ponds & water ways.
Withdrawal period: Meat *8 days, milk ***0 days.
Standard: **0 mg/tab
Packing: 5 bolus/blister * *2 plates/box * *0/box
Storage: store in a dry place below *5℃, protected from light. Keep all medicines out of children.
Shelf life: three years