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連絡先担当者 Winne
Wuhan, Other
| Product Name | TRV**0(Oliceridine) |
|---|---|
| Iupac Chemical Name | [(*-Methoxythiophen**-yl)methyl]({*-[(9R)**-(pyridin**-yl)**-oxaspiro-[4.5]decan**-yl]ethyl})amine |
| Synonyms | TRV***0,TRV**0,TRV **0;Oliceridine |
| Molecular Formula | C*2H*1ClN2O2S |
| Molecular Weight | **3.*1 |
| Smile | |
| InChiKey | DMNOVGJWPASQDL-OAQYLSRUSA-N |
| InChi | InChI=1S/C*2H*0N2O2S/c*****************9(*8)*************1(****************0)**********2(****1)*********2/h2,**7,*2,*5,*3H,**4,***1,****4,****7H2,1H3/t**-/m1/s1 |
| Cas | ***********7 |
TRV **0 Hcl is a novel -opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling(pEC*0=8.1), with potency and efficacy similar to morphine, but with far less -arrestin recruitment and receptor internalization.
The drug, recently granted FDA breakthrough therapy designation, has entered phase III clinical development as a treatment for acute pain
