RNASE T2
(ribonuclease T2) is an enzyme belonging to RNASE T2 family,
which is expressed in large quantities in temporal lobe and fetal
brain. RNASE T2 gene is a new member of extracellular ribonuclease
Rh / T2 / s-glycoproteins. It is a single copy gene. It is located
in the gene map of a region 6q27 related to human malignant tumors
and chromosome rearrangement. The absence of RNASE T2 is the cause
of leukocystopathy without megacephaly, which is a childhood
syndrome of leukoencephalopathy. It can affect the development of
neonatal microcephaly and neurological abnormalities, including
psychomotor disorders, epileptic seizures and sensorineural hearing
impairment. The brain shows multiple leukoencephalopathy, anterior
temporal subcortical cyst wall, abnormal myelin sheath development
Ventricular enlargement and intracranial calcification.
RNASE T2 provided by our company is a gene recombinant product
expressed in mammalian cells, with high purity, excellent
immunogenicity and biological activity.
General information:
Expression host: HEK293 mammalian cell
Source: a DNA sequence encoding the extracellular domain of human
RNASE2 (NM_ 003730.4)
Preservation buffer: PBS (pH7.4)
Molecular weight: about 36-42 KDa (SDS-PAGE detection)
Purity: ≥ 95% (SDS-PAGE detection)
Storage conditions: 4 ℃ for short-term storage or - 20 ℃ for
long-term storage, try to avoid repeated freezing and
thawing
Transportation conditions: ice bag with low
temperature
Safety tips: not for human experiment
