Povidone iodine

タイトルまたは説明

PVP-IODINE (povidone-iodine) disinfection drugs

Introduction
As a non-metallic elements necessary by French scientists in ***2 discovered Courtois, due to its deep purple steam in ***4 by the Cuy-Lussac name, derived from the Greek word "ioeides", meaning purple.
In medical practice, iodine was first used as a therapeutic drug for bronchitis (Halliday, ***1), ***9 was first used as a cure for wounds (Davis, ***9, Boinet***5). ***0, with "iodine" in the form approved by the U.S. Pharmacopeia. ***4, iodine was found to be one of the most effective sterilization, but its unpleasant odor and stain the skin making it unsuitable for practical use. In addition, iodine to human and animal tissue irritation, and iodine solution is unstable.
To the end of the last century, scientists have developed a series of iodine compounds and preparations, used to overcome the side effects of iodine, such as in an open wound causing pain and possible allergic reactions. Aimed at reducing the bactericidal effect is not significant in the case to avoid incompatibility. Therefore iodine carrier such as an ISP's PVP iodine, has become an ideal application form.
The general characteristics and advantages
Fifties, PVP iodine (povidone-iodine) as a fungicide used in the pharmaceutical market for a broad spectrum of pathogenic microorganisms, it is as effective as iodine itself. And iodine is different, PVP iodine less irritating to the skin and does not dissolve iodide or ethanol. In addition, PVP iodine stains can be washed. Early promotional materials will PVP iodine as "moderate iodine", because of its safety. Also, products containing PVP iodine iodine product does not require toxic label.
PVP iodine in human and veterinary medicine can be used, used to kill a variety of bacteria, germs, fungi, protozoa and yeast, for the suppression of certain insects are equally effective, but not PVP iodine resistant coverage.
Meanwhile, compared with the conventional iodine, PVP iodine safer, easier to use and lower systemic toxicity. The iodine solution is different, it does not sensitization, the use in the wound and mucous membranes does not cause pain. PVP iodine formed thin film to protect the open wounds, and this film can be washed with water, will not stain the skin for a long time, fiber or hard surface. PVP iodine particularly easy to use, because it is soluble in water and organic solvents such as ethanol. It can be in powder, tablets, troches, solutions, lotions, gels, ointments, creams, mousses or sprays carried formula.
PVP iodine prolonged non-specific antibacterial activity of microorganisms on the surface with superior effect on the treatment of mixed infections are particularly effective. PVP iodine has been demonstrated clinically in human and veterinary medicine in a variety of external validity.